Confirmation of the safety of combined oral contraceptives containing oestradiol on the risk of venous thromboembolism

Hormonal contraceptives, in particular combined oral contraceptives (COCs), were designed to avoid unintended pregnancy, with the fewest possible side effects and health risks. The most important and relevant adverse effect of COC use, although very rare, is the occurrence of venous thromboembolism (VTE). The oestrogenic component of COCs, traditionally ethinylestradiol (EE), is largely responsible for … Read more